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lavendustin A
CAS No. 125697-92-9
lavendustin A( Lavendustin A | RG 14355 | RG-14355 | RG14355. )
Catalog No. M17228 CAS No. 125697-92-9
lavendustin A is a potent, cell-permeable inhibitor of epidermal growth factor receptor (EGFR) tyrosine kinase.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 312 | In Stock |
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| 5MG | 537 | In Stock |
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| 10MG | 767 | In Stock |
|
| 25MG | 1161 | In Stock |
|
| 50MG | 1557 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
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| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product Namelavendustin A
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NoteResearch use only, not for human use.
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Brief Descriptionlavendustin A is a potent, cell-permeable inhibitor of epidermal growth factor receptor (EGFR) tyrosine kinase.
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DescriptionLavendustin A, also known as RG 14355, is a potent, cell-permeable inhibitor of epidermal growth factor receptor (EGFR) tyrosine kinase (IC50 = 11 nM). Lavendustin A shows cytotoxic effects on tumor cell lines. Lavendustin A enhances axon elongation in VHL gene-transfected neural stem cells.
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In Vitro——
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In Vivo——
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SynonymsLavendustin A | RG 14355 | RG-14355 | RG14355.
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PathwayEndocrinology/Hormones
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TargetCaMK
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RecptorEGFR
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Research Area——
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Indication——
Chemical Information
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CAS Number125697-92-9
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Formula Weight381.38
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Molecular FormulaC21H19NO6
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Purity>98% (HPLC)
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SolubilityDMSO : ≥ 250 mg/mL 655.51 mM
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SMILESO=C(O)c1cc(N(Cc2cc(O)ccc2O)Cc2ccccc2O)ccc1O
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Chemical Name5-[[(2,5-Dihydroxyphenyl)methyl][(2-hydroxyphenyl)methyl]amino]-2-hydroxybenzoic acid
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Nam DH, et al. Synthesis and anticancer activity of chromone-based analogs of lavendustin A. Eur J Med Chem. 2010 Sep;45(9):4288-92
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